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I like to think Miyazaki's interest in the pudgy mammals comes from the fact that they look inherently funny (or he draws them so), are a reminder of our fleshy smelly greedy corporeal selves, and yet smarter than we assume (They can learn tricks, solve problems, and in one experiment is taught to move a cursor using a modified joystick)
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The mechanism behind this increased risk involves carcinogens in tobacco smoke that damage the DNA of esophageal cells, promoting abnormal growth and cancer formation
Interestingly, HBV+DEN treatment led to significantly greater DNA damage, as indicated by H2AX + cells in the liver, compared with Sham+DEN at 4 months post-infection (Supplementary Fig
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