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However, bupropion potently inhibits CYP2D6, significantly increasing plasma concentrations of SSRIs metabolized through this pathway, including fluoxetine, paroxetine, and sertraline
Three medicines have been approved by the US Food and Drug Administration to help people break their addiction to nicotine, but smoking cessation rates remain low at about 15 per cent even though some studies say up to 70 per cent of smokers want to quit
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