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These include a plasma half-life of around 4.8 h on average, a peak plasma concentration of about 12 h after dosing, a clearance of between 2 and 5 mL/min/kg, a volume distribution of approximately 1.6 L/kg, a t of about 3.6 h, reaching a brain concentration between 2 and 10 nM

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on the other, the World Health Organization (WHO) warns of their potential harms, particularly for non-smokers and the youth, with the vaping rates of children and young people exceeding those of adults in most nations