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Additionally, smoking tobacco forms carbon monoxide (CO), which replaces oxygen in the red blood cells when inhaled

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There is some evidence that the deposition of the particles produced by cigarette smoking is different to that due to biomass or occupational exposures as these are mostly inhaled nasally where the filtration efficiency is higher, whereas tobacco smoke is inhaled through the mouth at a high flow rate leading to greater deposition in the lower airways and alveoli [22]

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As your body absorbs nicotine from chewing tobacco through the oral mucosa, it immediately travels toward your brain and activates hormones and transmitters that help soothe your senses, alleviate pain, and relieve any negative feelings you may have