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Arterioscler Thromb Vasc Biol 16(4):546552 Jaimes EA et al (2004) Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation

A pipe is a delicate piece of equipment, and a beauty that deserves respect

Nicotine also triggers the release of endorphins, your bodys happy drug and a natural painkiller

Metabolic re-patterning in COPD airway smooth muscle cells

Tobacco use may cause problems (for example, hypertension, vascular alterations) that lead to shortness of breath or chest pain that may be life-threatening

The question is, is the additional 100+ worth it for other options