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This statement from the Christian Medical and Dental Association is wise: CMDA maintains that a reasonable and prudent physician should only recommend FDA-approved pharmaceutical-grade medications when the indications are clear, dosing is well-established, risk-benefit ratios have been investigated and can be applied to individual patients, delivery systems are safe, and careful monitoring is agreed upon

However, as Mehrotra points out, They have been shown to have some effectiveness, but the impact can diminish over time

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