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In summary, the presence of macrophages in the TC models resulted in an earlier and more pronounced inflammation, lipid alteration and EMT response to CS exposure, highlighting the critical role of these cell types in mediating the cellular response to CS exposure

Moreover, we found LC3 II and p62 expression (Fig

NEWS AND VIEWS Healthy cells in smokers lungs have a high burden of mutations, similar to the mutational profile of lung cancer

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