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It enhances the chance of heart disease and lung cancer, weakens the immune system, and respiratory disorders

European Journal of Psychiatry

Though context-dependent, the meme is generally used to convey worry, anxiety, intense attention, fixation, or tension around a high-pressure topic or situation, often a reaction to an online discussion or thread

The advantage of that idea was that nobody would feel inclined to inspect the turn-out too closely if they saw it hangin' round the churchyard at unearthly hours

Imperial Brands - United Kingdom 11.4

The influence of heart rate on augmentation index and central arterial pressure in humans