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Globally, the use of e-cigarettes has surged, largely driven by aggressive marketing and widespread availability 4

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Users were instructed to "exhale the lungs of air, then after taking a mouthful of smoke, inhale the air into the lungs through the mouth allowing the smoke to go down with the air filling the lungs." Users were warned to "discontinue use if rapid pulse or blurring of vision appears." The label also warns that the inhalers are "not to be taken by elderly people except on competent advice." Although the product first appeared in the 1890s, ads promoting it as a treatment for asthma could be found into the 1950s

Kao CC, Hsu JW, Bandi V, Hanania NA, Kheradmand F, Jahoor F

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however, this could be related to growth outcomes in the fetus