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Results Cigarette smoke exposure impairs autophagic flux in macrophages Firstly, the impact of CSE exposure on the autophagic markers p62 and LC3, which were quantified by Western blot, were investigated in macrophages using phorbol 12-myristate 13-acetate (PMA)-dependent differentiated macrophage-like human U937 cells
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Some conditions that may develop depending on the affected brain areas are Alzheimers disease, frontotemporal dementia, chronic traumatic encephalopathy, Lewy body dementia, and limbic predominant age-related TDP-43 encephalopathy
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They redefined Americas new government, and, for a time there, Cheney got his hands right on the captains wheel