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First 12-Month Follow-Up of Psilocybin for Major Depressive Disorder 2022 One year after receiving psilocybin-assisted therapy for major depressive disorder (n=24), 75% of our participants showed a clinical treatment response (reduction of symptom severity by 50% or more) and 58% were in remission

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We confirmed in patch-clamp recordings that continuous 5 ms-light pulses at 8 Hz (470 nm) reliably increased VTA DA neuron activity in CatCh-transduced mice (Fig

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