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One unique thing about cannabis is that on the same day, I may have somebody who is 26, smoking four times a day, graduated from a local elite university, and not making it like they want to be making it

All of this might be worth it if there were a major health payoff

Alternative technologies Other smokeless nicotine delivery systems are already on or approaching the market, for example Ploom

One-way ANOVA (with Tukey post hoc test for comparison of multiple means) or, where appropriate, equivalent non-parametric KruskalWallis test (Dunn multiple comparisons) was used as specified in the figure legends

If you are prescribed the delayed-release version, take it once a week on the same day each week

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