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The nicotine is consumed gradually, not in a single sitting which is why the content-based comparison overstates the acute risk while the puff-based comparison overstates the daily intake
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Upper respiratory allergic disease appears extremely unusual indeed, and it is far more likely that any problem with nasal discharge or sneezing is due to infection in the nasal cavity/sinuses (although there is some debate about the exact anatomical distinctions here)
1AC and Supplementary Fig
