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The majority of naltrexone pharmacogenetic studies have examined the role of rs1799971 (or Asn40Asp), a SNP in the gene encoding the mu-opioid receptor ( OPRM1 ), as a moderator of treatment response

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Always follow manufacturer guidelines

[8] Some areas have found that Tobacco 21 policies can be developed and adopted in a shorter time frame and with fewer resources, can be targeted to a smaller group of stakeholders, and are perceived as less politically risky than other tobacco control measures such as smoke-free policies