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2020;4: CD000031 NICE guideline [NG92]: Stop smoking interventions and services (2018) Hartmann-Boyce J, and others

Although there were other differences, such as darkening of lower lids, wrinkles across the forehead, frown lines, crows feet and lines on the lower lips with accentuated puckering, none of these showed a statistically significant difference between the smokers and non-smokers evaluations

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We are therefore not able at this point to assess whether the reduced gestational length also corresponds with poorer infant health outcomes

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