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Cigarette smoke can make you sick since it contains thousands of toxic chemicals, which are known to irritate your respiratory system as well as affect your bodys oxygen levels

Ochs-Balcom HM, Grant BJB, Muti P, Sempos CT, Freudenheim JL, Browne RW, et al: Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD