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Clin Cancer Res 13:46864694 Zhang C, Ding XP, Zhao QN, Yang XJ, An SM, Wang H, Xu L, Zhu L, Chen HZ (2016) Role of 7-nicotinic acetylcholine receptor in nicotine-induced invasion and epithelial-to-mesenchymal transition in human non-small cell lung cancer cells

A 2023 study of trends in nicotine strength among e-cigarette products found that the average concentration of nicotine in e-cigarettes has increased from 2.5% to 4.4% between 2017 and 2022

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They ceased operation in 2018 after 65 years of operation