tobacco dust shafer's sign vitreous The Shaffer sign, also known as “tobacco dust,” is a clinical finding seen in retinal detachment. It refers to the presence of small, pigmented cells or pigment clumps in the anterior vitreous, Vitreous Opacities: Benign or Serious?

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The structure has stood the test of time and, though in some ways arbitrary, is still regarded as more useful for general epidemiological purposes than any of the alternatives tested (Sec

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This study was funded by the National Center for Advancing Translational Sciences, T32TR004543 Ethics declarations Competing interests The authors declare no competing interests

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