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Established knowledge and methods for cigarettes often drive content and emissions research, so new toxicants can be missed (ie, we may not know what to look for)

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Available at: Accessed June 15, 2005

How Does the Central Nervous System Play a Role

Philip Morriss research into EEG, PREP, and CSERP shows that the tobacco company attempted to quantify impact and to monitor the neurological effects of specific additives to maximize cigarette acceptance (which encompasses factors such as cigarette satisfaction and is influenced by a number of elements, including primary reinforcement [e.g., nicotine addiction] and secondary reinforcement115)

The primary ingredient in tobacco is nicotine