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Those with higher nicotine tolerance may opt for strengths up to 24 mg/mL for a more satisfying experience

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The researchers found that 49% of the participants in the abrupt-quit group were not smoking by one month after their quit day, compared with 39.2% in the gradual-quit group

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Varenicline works by binding to dopamine receptors and blocking the positive effects of nicotine, thus reducing the pleasure and cravings of smoking