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On the issue of "clinical efficacy" (in cessation studies, normally how well a quitting product performs against quitters "unknowingly" assigned to use an inert placebo product or device), since Mooney's 2004 "Blind Spot" study, the FDA has been unable to deny full awareness that attempts to blind participants as to active or placebo group assignment in randomized NRT studies have been a sham

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They also reported how much nicotine was in their vaping liquid

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For example, nicotine patches come in strengths of 552.5mg, which is slowly taken up through the skin over the course of a day