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E-cigarettes do contain nicotine which, though it creates dependence, does not pose a major health risk, the US FDA has said while participating in the public debate on the effect of vaping on health

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Subgroup findings Only four single-sex-based animal studies 29,49,51,52 were found analyzing oxidative stress in the lung, of which three studies were conducted in male mice 29,49,51 and one study in female mice 52

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