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The study design placed non-smokers in a sealed, unventilated chamber with experienced cannabis users who smoked high-potency marijuana (up to 11.3% THC)

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Surely the danger posed to the smoking masses was not the mild and soothing weed, he wrote, but the organized creation of states of frantic alarm. Fisher was a well-known hothead (and an inveterate pipe smoker), but the letter and the resulting debate, which lasted until his death in 1962, was taken as a serious critique by the scientific community