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"There's the very big concern of the so-called gateway effect, that it leads people on to feel familiar with smoking and then to think of taking up tobacco cigarettes, so there are multiple levels of harm," Professor Kelso said

1 in seven countries upon release

[1] [2] [8] [9] [10] [11] [12] Beyond Russia and the United States, the brand has been sold in other global markets, including but not limited to Austria, Poland, Hungary, the Czech Republic, Serbia, Estonia, Latvia, Lithuania, Belarus, Ukraine, Kazakhstan, South Africa, Romania, Mongolia, Taiwan, and Jordan

The most effective smoking cessation tools include the medication varenicline (Chantix), the plant-derived cytisine (not available in the US), and nicotine-containing e-cigarettes