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While many flavor chemicals in EC are reported safe for use in food 2 , the National Institute for Occupational Safety and Health has warned food-processing workers that some inhaled flavor chemicals may cause lung disease 3 , and the Flavor and Extract Manufacturers Association has strongly cautioned that their Generally Recognized as Safe (GRAS) certification is intended for exposure by ingestion, not inhalation 4

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Yes, body weight and metabolism can influence how the drug is processed