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While Kaczynski et al

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adults, particularly among populations with the highest rates of use

The uncertainties in understanding all of the factors involved in the delivery and uptake of toxic, carcinogenic, and addictive chemicals in cigarette smoke and the mechanisms of toxicity induced by cigarette smoke should not impede efforts to lower the concentrations of these chemicals in cigarette smoke

The mortality rate 5 years after an oral cancer diagnosis is 43%

Smoking was considered for its morale boosting qualities among soldiers and civilians