cigarette science Creating a smoking machine — Harvard Gazette Chemicals in Cigarettes and Tobacco:

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Nicotine causes the release of dopamine chemical, which makes us simultaneously active, alert and relaxed

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Entertainer Frank Sinatra smoking a cigarette during a rehearsal

That can lead to the development or worsening of eye conditions like macular degeneration, cataracts, glaucoma, diabetic retinopathy, thyroid eye disease, or damage to the optic nerve (the cord connecting the eyes to the brain)