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This is because smoke particles (like from cigarettes) tend to be between 0.1 and 1.0 microns in size, but a True HEPA filter can remove 99.97% of particles up to 0.3 microns in size

The FDA says the proposal would reduce disease and death by helping current smokers quit and stopping younger people from starting.Stanford Research Into The Impact Of Tobacco AdvertisingAn advertisement for Marlboro Menthol cigarettes

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Do not use ozone generators in occupied spaces

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In an enclosed area, like the inside of a vehicle, removing the odour can be even more problematic