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Because the disease caused them to expel all their food, whether, through the mouth or elsewhere, cholera would weaken people until they no longer had the strength to fight back

This is in reference to Miguel O'Hara/Spider-Man 2099, who was voiced by Oscar Isaac in the Spider-Verse sequel

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Background Every year 5,6 trillion cigarettes are smoked, of which 4,5 trillion end up in the environment

In this study, scientists found that the older the device, the more toxic the emissions are