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For the purpose of this discussion, we will focus on substances that are commonly referred to as gateway drugs: caffeine alcohol tobacco marijuana Caffeine Image 4.2 Hot Coffee in a White Mug Surrounded by Coffee Beans on a Wood Table History and Background Caffeine is a bitter substance that occurs naturally in more than 60 plants, including coffee beans, tea leaves, kola nuts (used to flavor soft-drink colas), and cacao pods (used to make chocolate products)

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including smoking accessories such as pipes, rolling papers, filters), along with tobacco substitutes (E-cigarettes, JUULs, vape liquids, vape pens, tanks, and disposable devices) to anyone under the age of 21

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WHO Framework Convention on Tobacco Control, Article 13 (Tobacco advertising, promotion and sponsorship) calls for comprehensive bans on tobacco advertising, promotion and sponsorship in accordance with each country's constitutional principles