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These are chemicals that are teratogenic, which means they may be tolerated by adults but the fetus cannot tolerate them. The underlying mechanisms behind these harms are not clear from the research, but e-cigarettes contain hazardous heavy metals such as lead, cadmium and nickel, as well as other additives like polyethylene glycol and diacetyl, an artificial flavouring agent implicated in a non-cancerous lung injury called popcorn lung. Some chemicals that are safe to ingest may not be safe when vaporized and inhaled into the lungs, the researchers posit, calling for further study

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