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DISCUSSION To better understand the metabolic differences in smokers who smoke cigarettes with low and high nicotine content, untargeted metabolomics and bioinformatics analyses were used to assess the metabolomic profiles of urine samples

Jonathan Samet from the University of Southern California and the editor of the article recently advised the California State Legislature that it is evident that filtered cigarettes have had little impact on the risks of smoking over the last half century. Because existing anti-littering laws have not changed smokers littering habits, Novotny and Slaughter ask for new environmental interventions and partnerships between tobacco control and environmental groups

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