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Alveolar Type II Cells (ATII) isolated from patients with emphysema exhibited severe mtDNA damage and excessive mitochondrial superoxide production, along with reduced p-Drp1, FIS1, and MFN2 levels, suggesting that mtDNA damage leads to abnormal mitochondrial dynamics (Kosmider et al., 2019)

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Behavioral effects of acute and chronic imipramine in the elevated T-maze model of anxiety

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