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Acetaldehyde was shown to alter cellular respiration in cultured microvascular endothelial hBMVEC cells, which mainly comprise the bloodbrain-barrier, thereby suggesting negative effects on bloodbrain-barrier integrity (121).Further, in cultured primary cortical neurons, acetaldehyde impaired mitochondrial respiration via NOX -mediated activation (122), and in brain mitochondria in vitro , acrolein inhibited mitochondrial respiration via complex I (123)
Original Publication: Picture Post Ad - Vol 64 No 15 P 51 - pub
Details Category: Smoking Collection: Sir Henry Wellcome's Museum Collection Object Number: A652833 Materials: bowl, briar, band, metal, electro plated nickel silver, mouthpiece, resin, case, leatherette, velvet and brass Measurements: overall: 55 mm x 161 mm x 61 mm, .07kg pipe: 48 mm x 121 mm 36 mm, .04kg type: briar tobacco pipe credit: Wellcome Trust (Purchased from Stevens)
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