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4547 However, because these studies specifically excluded patients with severe, underlying cardiac diseases, the clinical practice guideline 37 recommends that because of a lack of safety data in these higher-risk populations, NRT should be used with caution among patients who have experienced a myocardial infarction within the past two weeks and among those with serious arrhythmias or unstable angina

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An estimated 40 per cent of EU citizens would face cancer at some point in their lives, with an annual economic impact estimated around 100 billion euros (87 billion)

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