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Stepwise one-electron reductions of O 2 yield O 2 , which yields hydrogen peroxide (H 2 O 2 ) and finally converts to OH ( 2 O 2 produced from O 2 can be detoxified by mitochondrial or cytoplasmic catalase or can yield the highly diffusible H 2 O 2

Beyond their unknown long-term effects on human health, the extended list of appealing flavours available seems to attract new never-smokers, which is especially worrying among young users

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Bacterial diversity was reduced at lower doses (2.5 mg) but increased at higher doses (250 mg)

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