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It began as a functional solution

Anatomical Structures Involved Proximal airways (trachea, main bronchi): Goblet cell hyperplasia, mucus hypersecretion chronic bronchitis phenotype (J41.x, J42) Peripheral airways ( 1/3 hemithorax)

Interference with Hormonal Balance Smoking also modulates the oestrogen metabolism, and this could influence the cervical environment, leading to abnormal cell growth

[DOI] [PubMed] [Google Scholar] Smith 2003 Smith SS, Jorenby DE, Leischow SJ, Nides MA, Rennard SI, Johnston AJ, et al

The interplay between respiratory microbiota and innate immunity in flavor e-cigarette vaping induced lung dysfunction

The following interview has been edited and condensed from that conversation, and includes additional questions from a follow-up phone call in August