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When they start to "wander", they are about to pupate, so are placed in a pupation chamber

In this scenario, the goal is improved public health, and the means is a cigarette tax increase

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Samples were prepared in triplicate at 50 mg/mL in a mixture of methanol/water (70:30) containing deuterated internal standards (myosmine-d 4 , cotinine-d 4 , nornicotine-d 4 , and anabasine-d 4 )

Because of this variability, the impact on treatment response is difficult to predict

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