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The CYP2D enzyme family is a well-documented major metabolizer of antidepressants, including desipramine, doxepin, imipramine, maprotiline, mianserin, nortriptyline, protriptyline, and trimipramine (168)

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However, NHS research shows that only 3 in every 100 smokers manage to stop smoking permanently by going 'cold turkey'

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Inhalation of cigarette smoke exposes humans to cadmium, a highly toxic metal that is linked to a variety of serious illnesses, including cancer