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Similarly, in adults with obesity and T2D, the 7.2mg dose resulted in an average 13% weight loss compared to 10% with 2.4 mg and 3.9% with placebo, along with significant reductions in blood sugar levels and waist size

[DOI] [PMC free article] [PubMed] [Google Scholar] 167.Esposito M., Giunta A., Nanni R.C., Criscuolo S., Manfreda V., Del Duca E., Bianchi L., Troisi A

Significant metabolites (biomarkers) were selected by analyzing loadings and variable importance in the projection (VIP) plot from the OPLS-DA model, indicating the variables crucial for group discrimination

IR refers to the decreased responsiveness of insulin-target tissues to physiological levels of insulin, which is a common feature of PCOS (39), although it is not included in the diagnostic criteria for PCOS

Tao J, Deng H, Li Z, Cao L, Rao Y, Yin Z