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The earliest cultural evidence of cannabis use dates from 4800 BCE and involves the Yangshao, a Neolithic culture in China that appeared along the Yellow River Valley [11]

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However, the report which cannot distinguish between cigarettes, nicotine patches and vapes also warned of a short-term increasing trend in nicotine consumption that's been emerging since 2022

[96] [97] [98] The goal of tobacco companies also drives the widespread use of flavored tobacco products