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82 Similarly, the Roflumilast Effect on Exacerbations in Patients on Dual (LABA/ICS) Therapy (RE 2 SPOND) study recruited 2254 patients with a nearly identical clinical profile as the REACT trial and randomized them to the U.S

Int J Environ Res Public Health 13(11):1123 Kim SY, Jeong SH, Joo HJ, Park M, Park EC, Kim JH et al (2022) High prevalence of hypertension among smokers of conventional and e-cigarette: using the nationally representative community dwelling survey

It affects more than 3 million people in the United States

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