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Curosurf (poractant-alpha, Chiesi Farmaceutici, Parma, Italy) is a clinical surfactant preparation provided as a suspension at 80 mg/mL containing more than 90% of surfactant phospholipids and around 1% by mass of surfactant proteins SP-B and SP-C

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These data are clinically relevant as in vitro cisplatin resistance has been reported to be predictive of cancer chemoresistance in patients 38 , and resistance to platinum-based chemotherapy is one of the main factors contributing to poor patient prognosis 48

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