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Unless otherwise specified, all analysis of scRNA-seq and scTCR-seq data throughout this study were performed using R (version 4.4.0)

The tobacco industry has been making strides in terms of the products they design and manufacture, catering to the varying preferences of nicotine and tobacco users all over the world

Similarities between the two have been pointed out, such as the mysterious, enigmatic nature they share, the references to smoking present in Half-Life: Alyx , and spoken lines themselves, G-Man's infamous line "Prepare for unforeseen consequences" bearing a slight resemblance to the Smoking Man's line "There have been unforeseen events"

ISSN 1470-2738

WHO calls on governments, civil society, and the public to unite in safeguarding the health and well-being of children and young people by strengthening tobacco control policies and supporting cessation efforts

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