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Other reported effects from prolonged use include: Dry mouth Anxiety and agitation, particularly during withdrawal Gut microbiome disruption in some users Nicotine overdose in new users who start with high-strength pouches Who should avoid snus and nicotine pouches, or speak to a clinician first: Pregnant or breastfeeding individuals (nicotine affects fetal and infant development) People with heart rhythm disorders or uncontrolled hypertension (nicotine raises heart rate and blood pressure) Adolescents under 18 Anyone trying to quit nicotine entirely (approved cessation tools like patches, gum, or prescription medication are more appropriate) Start with strengths between 4-8mg per pouch if you're new to snus or nicotine pouches, and adjust based on your cravings and tolerance

Genetics play a large role too: some people inherit a tendency to high LDL, and an inherited condition called familial hypercholesterolemia can cause very high levels early in life

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The deadline for resumes is July 31

The board thanks Howard for his nearly 30 years of distinguished service to Altria and for helping to set the course for Altrias 10-year vision to responsibly lead the transition of adult smokers to a noncombustible future, Farrell said