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The interplay between cigarette smoking, autophagy and macrophage function has also been reported, with alveolar macrophages from smokers showing accumulation of autophagosomes and protein aggregates due to defective autophagic flux 14

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2-Minute Neuroscience: Nicotine Chemistry Nicotine is an alkaloid that is found in certain plants, such as the Nicotiana tabacum plant that is used to produce tobacco products