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As per a recent study, during 20152019, there were 165 803 900 SLT users across SEAR, with 479 466 attributable deaths annually, of which India accounted for 79.9%, with 383 248 deaths

PMID 21768054

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Among other things, the report found that providers incur additional costs associated with delivering clotting factor that are not separately reimbursed by Medicare. Specifically, the report cited delivery costs generated in inventory management, specialized refrigerated storage, shipping, and the provision of ancillary supplies such as needles, syringes, and tourniquets to patients that were not accounted for by Medicare payment for the clotting factor product alone