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The FDA also remains focused on its regulatory oversight of e-cigarettes and other electronic nicotine delivery systems (ENDS)

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[PubMed: 7781690] Eaker DW

Inadequate basis for claiming that flavors cause vaping uptake In section 1 above, we show why it is inappropriate in the context of APPH to assume that ENDS uptake is harmful to youth

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The in vitro test battery comprising assays for bacterial mutagenicity, mammalian cytogenetics/mutation, and mammalian cytotoxicity, that has been suggested by a CORESTA task force in 2004 ( in vitro tests can specifically address smoking related adverse effects, as biphasic culture of airway epithelial cells or assays on endothelial activation as conducted by the manufacturers ( in vitro cultured lungs tissues are now available by several commercial suppliers