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Additionally, cells were exposed to 10% CSE for 3 months followed by 3 months culture in 0% CSE (referred to as -10% CSE)

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Introduction Peripheral artery disease (PAD) is a major cardiovascular disease that affects more than 200 million people worldwide and an estimated 8.5 million people in the U.S ( Smoking contributes to the clinical expression of PAD and smoking cessation has clear clinical benefits

these cells subsequently enter the arterial wall and promote atherosclerosis.95 In young adults who chronically used electronic cigarettes, FDG-PET CT showed increased uptake in the spleen and aortic wall compared with non-users, which is consistent with the engagement of the splenocardiac axis by the substances released by these devices.96 The effect on physical properties of the cardiovascular system come from a study of mice exposed to electronic cigarette vapours for 8 months (4 hours a day for 5 days a week, emulating an equivalent of 20 years of exposure in humans)