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All of this suggests that these companies are incredibly sophisticated, they know how to game this system and they are intentionally doing so, said William George, research director for ImportGenius

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Over time, the long-term effects of nicotine on the brain lead to the development of tolerance, requiring higher doses to achieve the same pleasurable effect, thus driving addiction

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Better understanding of those mechanisms could lead to better prevention and treatment strategies, especially among mentally ill smokers, Dr